top of page
Department of Life sciences
Research Publications
2023
Iris Grossman-Haham. 2023. “Towards an atomic model of a beating ciliary axoneme”. Current Opinion in Structural Biology 78
2021
Iris Grossman-Haham, Nicolas Coudray, Zanlin Yu, Feng Wang, Nan Zhang, Gira Bhabha, and Ronald D Vale. 2021. “Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating”. Nature Structural & Molecular Biology 28 (1): 20-28.
2020
Tal Feldman, Iris Grossman-Haham, Yoav Elkis, Patrick Vilela, Neta Moskovits, Iris Barshack, Tomer M Salame, Deborah Fass, and Tal Ilani. 2020. “Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models”. Oncotarget 11 (4): 386.
2019
Gabriel Javitt, Iris Grossman-Haham, Assaf Alon, Efrat Resnick, Yael Mutsafi, Tal Ilani, and Deborah Fass. 2019. “cis-Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures”. Protein Science 28 (1): 228-38.
2018
Iris Grossman-Haham, Gabriel Rosenblum, Trishool Namani, and Hagen Hofmann. 2018. “Slow domain reconfiguration causes power-law kinetics in a two-state enzyme”. Proceedings of the National Academy of Sciences 115 (3): 513-18.
2016
Iris Grossman, Tal Ilani, Sarel Jacob Fleishman, and Deborah Fass. 2016. “Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma”. Protein Engineering, Design and Selection 29 (4): 135-47.
2015
Iris Grossman, Haim Yuval Aviram, Gad Armony, Amnon Horovitz, Hagen Hofmann, Gilad Haran, and Deborah Fass. 2015. “Single-molecule spectroscopy exposes hidden states in an enzymatic electron relay”. Nature Communications 6 (1): 1-10.
2014
Yair Gat, Alexandra Vardi-Kilshtain, Iris Grossman, Dan Thomas Major, and Deborah Fass. 2014. “Enzyme structure captures four cysteines aligned for disulfide relay”. Protein Science 23 (8): 1102-12.
2013
Tal Ilani, Assaf Alon, Iris Grossman, Ben Horowitz, Elena Kartvelishvily, Sidney R Cohen, and Deborah Fass. 2013. “A secreted disulfide catalyst controls extracellular matrix composition and function”. Science 341 (6141): 74-76.
2013
Iris Grossman, Assaf Alon, Tal Ilani, and Deborah Fass. 2013. “An inhibitory antibody blocks the first step in the dithiol/disulfide relay mechanism of the enzyme QSOX1”. Journal of Molecular Biology 425 (22): 4366-78.
2012
Assaf Alon, Iris Grossman, Yair Gat, Vamsi K Kodali, Frank DiMaio, Tevie Mehlman, Gilad Haran, David Baker, Colin Thorpe, and Deborah Fass. 2012. “The dynamic disulphide relay of quiescin sulphydryl oxidase”. Nature 488 (7411): 414-18.
bottom of page